Best Adrenal Fatigue Supplements – Top 3 Products To Buy In 2021

Supplement expert Dale Janic rounds-up the best supplements for adrenal fatigue out there today. Here’s the top 3 picks for 2021 plus everything you need to know when shopping in our detailed buyer’s guide.

Best Adrenal Fatigue Supplements

There’s no doubt that at some point in just about everyone’s life they have had a stressful experience.

You may have been stressed out as a result of an illness, your job, a death in the family, your children or any other life changing event.

Stress can actually be caused by any type of physical or emotional overload and it may make you feel as if there’s no way to get yourself together.

Or at least you feel like you just can’t get back to your normal every day comfort zone.

The 3 Best Adrenal Fatigue Supplements

So now we’ve established that chronic elevated stress levels is not at all healthy and can lead to adrenal fatigue as well as a number of chronic conditions.

And a great way to manage stress and adrenal issues is by ensuring that you are getting the proper nutritional support.

Getting the right doses of adrenal support from B-Vitamins, Vitamin C and a multivitamin/mineral complex doesn’t have to be hard to figure out though.

That’s why I put this list of the top adrenal fatigue supplements.

You can get the support you need without having to buy several separate supplements.

1. Diazaprin

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In today’s fast paced world, people are suffering from the affects of stress and anxiety more than ever before.

This has led to the dramatic increase in anti-anxiety medication prescriptions being written every day.

But prescription medications can cause more harm than help, as seen on every prescription advertized on television.

Plus, most herbal over the counter supplements simply don’t offer the level of support that someone dealing with chronic stress and anxiety levels needs.

This is where Diazaprin can help.

What is Diazaprin?

Diazaprin was developed specifically by Lazarus Labs, the leaders in over the counter nutraceuticals, to combat stress and anxiety that can lead to adrenal fatigue.

This is not an ineffective herbal product that can’t deliver, either.

Diazaprin is a scientifically developed nutraceutical and one the most powerful and effective adrenal support supplements you can buy without a prescription.


When taken as directed, Diazaprin can offer a complete solution to stress management and adrenal support.

This product contains one of the most complete blends of specific ingredients that can:

  • Help diminish stress and anxiety
  • Help you to calm down and relax
  • Help you feel more calm and in control
  • Help prevent panic attacks
  • Provide your adrenals with the support they need


Diazaprin is comprised of a complete blend of ingredients that work synergistically for one of the best anti-stress and adrenal support formulas on the market today.

It also contains crucial B-Vitamins and minerals that were discussed above, which are important for adrenal support.

The ingredients include

  • Vitamin B-1 (Thiamine HCl)
  • Vitamin B-2 (Riboflavin)
  • Niacinamide
  • Vitamin B-6 (Pyridoxine HCl)
  • Folic Acid
  • Vitamin B-12 (Cyanocobalamin)
  • Calcium (Carbonate)
  • Magnesium (Oxide)
  • Ashwagandha Root
  • GABA (Gamma-Aminobutyric Acid)
  • Chamomile Flower
  • 5-HTP (5-Hydroxytryptophan)
  • DMAE (Dimethylaminoethanol Bitartrate)


The dosage is one tablet and for best results, Diazaprin should be taken 1 to 2 times daily. The manufacturer recommends taking this supplement with meals or as directed by your healthcare professional.

Additional Considerations

So if you lead a particularly stressful life, experience chronic fatigue along with the inability to focus, Diazaprin is the supplement for you.

Diazaprin can help your body to better deal with extreme stress and overcoming the debilitating effects of Adrenal Fatigue.

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2. Adrenal Revive

Adrenal Revive was developed to specifically treat the signs of adrenal fatigue by supporting optimal adrenal gland function.

How It Works

Adrenal Revive helps restore damaged adrenal gland function, empowering the adrenal glands to function at their highest level possible.


Adrenal Revive helps your body feel a renewed energy and sustains that energy throughout the day.

While taking Adrenal Revive, you’ll feel energized, have stamina and be able to focus again.

  • Rebuild Adrenal Glands
  • Optimize Adrenal Hormone Production
  • Supports Adrenal Gland Function


The natural ingredients in Adrenal Revive include Licorice Root, known for its ability to help regulate the production of stress hormones in the adrenal glands and to boost energy levels and endurance.

The addition of CoQ10 promotes the production of several key enzymes that are used to create ATP, which is burned by your body for energy, thus increasing energy and helping your body function optimally.

Additional Considerations

Most individuals notice a difference in their energy levels within days of use and continue to feel better with each passing day, making Adrenal Revive one of the most popular products available.

3. Adrenal Cocktail + C

Along with promoting optimal adrenal gland function, Jigsaw Adrenal Cocktail™ from Jigsaw Health provides the additional nutritional support that your body needs.

The key is the addition of whole food Vitamin C, which is essential for optimum adrenal function.

If you are struggling with low energy and are overstressed, then Jigsaw Adrenal Cocktail™ may be the supplement for you.

How It Works

Jigsaw Adrenal Cocktail™ is a full-circle supplement to combat the effects of adrenal fatigue.

It helps your body perform at its best with the addition of important vitamins, minerals and electrolytes into the supplement, which is vital to healthy adrenal function.


When your body is receiving the nutrients it needs, it supports the healthy release of cortisol – the adrenal glands’ response to helping you deal with chronic stress and the cause of ongoing fatigue.

This supplement gives your body the nutrients it needs to help heal the adrenals as well as balance electrolytes.

Electrolytes such as Potassium work synergistically with Vitamin C to help lower cortisol levels.


Jigsaw Adrenal Cocktail™ contains a unique blend of ingredients to help the adrenal glands perform at their best.

It also provides extra nutrients that your body needs, such as Sodium and Potassium, so it can overcome the effects of adrenal fatigue.

The ingredients include:

  • Wholefood Vitamin C
  • Redmond’s Real Salt
  • Potassium Bicarbonate

Additional Considerations

Jigsaw Adrenal Cocktail™ continues to receive good reviews from consumers who have experienced renewed health and energy.

This is a good product and one of the only ones that takes into consideration including electrolytes into the formula

An Introduction To Adrenal Fatigue

After any stressful situation or event, most people may start to experience the effects right away.

You may start to experience things such as:

  • Feel tired upon waking up in the morning
  • Finding it hard to relax
  • Finding it hard to get motivated to exercise
  • Getting sick more frequently
  • Take an extremely long time to get well

All these side effects that can result from a stressful event can lead to what’s referred to as adrenal fatigue.

And adrenal fatigue caused by stress can even end up being a life-threatening condition if not properly managed.

What Is Adrenal Fatugue?

The adrenals are two triangle shaped glands that are situated over top of the kidneys.

The job of the adrenal glands is to regulate the hormonal release of cortisol during stressful events.

These hormones are used by the body to regulate different actions like heart rate, mental acuity and overall physical strength.

When high stress levels are few and far between this release of cortisol is not a problem.

However, when stress becomes chronic and cortisol is released continuously, this becomes a big problem.

The adrenal glands eventually become over-fatigued and are no longer able to keep up with pumping out the amounts of cortisol that are needed.

This also affects other hormonal regulations in the body and creates a domino effect.

This then becomes what we refer to as adrenal fatigue.

What Are The Symptoms?

There is a wide range of symptoms that you may experience but here is a list of the most common ones:

  • Anxiety
  • Depression
  • Food cravings (especially for sweets)
  • Low sex drive
  • Low body temperature
  • Insomnia
  • Overall body fatigue

The Best Adrenal Support Supplements

Luckily, there are several supplements for adrenal support and that are available over the counter to help deal with the condition.

These supplements can help tremendously not only in reducing stress, but also in nourishing and strengthening the adrenal glands.

Vitamin C

Vitamin C is one of the vital supplements for maintaining the proper function of the adrenal glands.

Vitamin C is a key component in the production of various adrenal hormones.

It has also been established that urinary excretion of vitamin C is generally higher during periods of high stress.

This means that you need to increase your Vitamin C intake during times of stress.

As a matter of fact, it’s been established in studies that increased doses of Vitamin C helps to minimize both the mental and physical response to stress and anxiety. [1]

Vitamin C is therefore a vital stress and adrenal support supplement.

It is advised to take between 2 grams and 6 grams of vitamin C daily for support.

In addition, experts advise to use supplements that contain bioflavonoids so as to maximize its absorption.


Other supplements that have been shown in studies to be essential in the management of adrenal fatigue and other stress related symptoms are B Vitamins. [2]

All B Vitamins are important for stress management because they are needed for the proper function of the adrenals and nervous systems.


According to medical professionals, a daily dose of a B-100 complex supplement should be taken with food for proper assimilation of the most essential B vitamins.

Another B vitamin supplement that is recommended for stress management and adrenal fatigue is B-5.

Vitamin B-5

Also known as Pantothenic acid, vitamin B-5 is particularly essential for stress reduction as well as adrenal support.

It is a component that is required by the adrenal glands for the synthesis of hormones.

In a nutshell, the adrenal glands cannot properly function without it.

Therefore, it is recommended to take an additional dose of 1,500 mg of pantothenic acid per day.

Multivitamin and Mineral Complex

A multivitamin and mineral complex is other important supplement for adrenal support.

Increasing your daily intake of vitamins and minerals is absolutely essential in periods of high stress levels.

This is because stress is known to deplete vital nutrients from the body that are required for proper functioning and balance.

According to two recent studies, people who took a multivitamin and mineral complex on a daily basis were able to cope better with stressful situations that those who took the placebos. [3]

It is recommended that you should choose a supplement that has a generous mixture of antioxidants such as:

  • Vitamin A
  • Vitamin E
  • Vitamin C
  • Calcium
  • Selenium
  • Zinc
  • Magnesium

This ensures you are getting the essential nutrients for proper adrenal support.


No matter how you decide to combat adrenal fatigue, I cannot overemphasize the importance of proper nutrition.

This is especially true when it comes to supporting the function of your adrenals.

So with that said, any of the supplements recommended above can have added benefits to your regimen for optimal adrenal health.

Give any of them a try and report back and let us know how they worked.

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